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COX15 anticorps (N-Term)

COX15 Reactivité: Humain, Rat, Souris, Lapin, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Saccharomyces cerevisiae, Cobaye, Cheval WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN310821
  • Antigène Voir toutes COX15 Anticorps
    COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))
    Épitope
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 26
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Lapin, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Saccharomyces cerevisiae, Cobaye, Cheval
    Hôte
    • 24
    • 2
    Lapin
    Clonalité
    • 25
    • 1
    Polyclonal
    Conjugué
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COX15 est non-conjugé
    Application
    • 13
    • 11
    • 10
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    DWHLIKEMKP PTSQEEWEAE FQRYQQFPEF KILNHDMTLT EFKFIWYMEY
    Homologie
    Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Yeast: 82%, Zebrafish: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against COX15. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human COX15
    Top Product
    Discover our top product COX15 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 388 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Swenson, Cannon, Harris, Taylor, Fox, Khalimonchuk: "Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes." dans: The Journal of biological chemistry, Vol. 291, Issue 19, pp. 10411-25, (2016) (PubMed).

  • Antigène
    COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))
    Autre désignation
    COX15 (COX15 Produits)
    Synonymes
    anticorps COX15, anticorps wu:fa18g06, anticorps zgc:56240, anticorps zgc:77422, anticorps 2900026G05Rik, anticorps CEMCOX2, anticorps COX15, cytochrome c oxidase assembly homolog, anticorps COX15 homolog, cytochrome c oxidase assembly protein (yeast), anticorps COX15 cytochrome c oxidase assembly homolog, anticorps cytochrome c oxidase assembly homolog 15 (yeast), anticorps cytochrome c oxidase assembly protein 15, anticorps cytochrome c oxidase assembly protein COX15 homolog, anticorps COX15, anticorps Cox15, anticorps cox15, anticorps LOC100410987, anticorps LOC100599631
    Sujet
    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates several transcript variants diverging in the 3' region including alternate poly A sites. In total, 2 different isoforms are encoded by these variants.
    Alias Symbols: -
    Protein Interaction Partner: UBC, CLN3, MRPS14, NDUFA12, TOMM7, MRPL15, LAMTOR3, SURF1, NDUFS8, NDUFS6, NDUFS4, NDUFA9, CYC1,
    Protein Size: 388
    Poids moléculaire
    44 kDa
    ID gène
    1355
    NCBI Accession
    NM_004376, NP_004367
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