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DDOST anticorps (N-Term)

DDOST Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Lapin, Mouton WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN310826
  • Antigène Voir toutes DDOST Anticorps
    DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))
    Épitope
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 30
    • 9
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval, Lapin, Mouton
    Hôte
    • 30
    • 4
    Lapin
    Clonalité
    • 31
    • 3
    Polyclonal
    Conjugué
    • 17
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DDOST est non-conjugé
    Application
    • 25
    • 13
    • 12
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    SPSVEDFGGN INVETISAFI DGGGSVLVAA SSDIGDPLRE LGSECGIEFD
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against DDOST. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST
    Top Product
    Discover our top product DDOST Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 456 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))
    Autre désignation
    DDOST (DDOST Produits)
    Synonymes
    anticorps AGER1, anticorps CDG1R, anticorps OKSWcl45, anticorps OST, anticorps OST48, anticorps WBP1, anticorps DDOST, anticorps wu:fa11d01, anticorps zgc:66068, anticorps zgc:77478, anticorps Ddost, anticorps CG9022, anticorps DmOST50, anticorps Dmel\\CG9022, anticorps DrOST, anticorps OST48/WBP1, anticorps Ots48, anticorps anon-EST:Liang-1.11, anticorps clone 1.11, anticorps ost48, anticorps dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit, anticorps dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) S homeolog, anticorps dolichyl-diphosphooligosaccharide-protein glycosyltransferase, anticorps dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic), anticorps dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, anticorps dolichyl-di-phosphooligosaccharide-protein glycotransferase, anticorps Oligosaccharyltransferase 48kD subunit, anticorps DDOST, anticorps ddost.S, anticorps GTR26, anticorps ddost, anticorps Ddost, anticorps LOC5580056, anticorps PTRG_01946, anticorps Ost48
    Sujet
    DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
    Alias Symbols: AGE-R1, KIAA0115, MGC2191, OK/SW-cl.45, OST, OST48, WBP1, AGER1, OKSWcl45
    Protein Interaction Partner: HUWE1, VAPB, UBC, FAF1, STAU1, ASB11, TRIM13, SUZ12, EED, CLN3, NXT1, SRSF11, FN1, ATF2, STT3B, MAGT1, ZMPSTE24, VDAC2, SSR4, SSR3, SLC25A3, ILF2, KRTCAP2, FBXO6, UBD, AMFR, AUP1, TMEM173, UNC93B1, MAPK6, HDAC5, AGO3, BRCC3, GSTK1, TMBIM4, PGRMC1, SAP18,
    Protein Size: 456
    Poids moléculaire
    46 kDa
    ID gène
    1650
    NCBI Accession
    NM_005216, NP_005207
    UniProt
    Q5VWA5
    Pathways
    Cell RedoxHomeostasis
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