ZMPSTE24 anticorps (N-Term)

N° du produit ABIN310835

Détail du produit anti-ZMPSTE24 anticorps

Antigène: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZMPSTE24 est non-conjugé

Application: Western Blotting (WB)

Séquence: LYSETEGTLI LLFGGIPYLW RLSGRFCGYA GFGPEYEITQ SLVFLLLATL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 91%, Zebrafish: 90%

Attributs du produit: This is a rabbit polyclonal antibody against ZMPSTE24. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ZMPSTE24

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 475 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ZMPSTE24

Antigène: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Autre désignation: ZMPSTE24 (Zmpste24 Produits)

Synonymes: anticorps DDBDRAFT_0189115, anticorps DDBDRAFT_0237846, anticorps DDB_0189115, anticorps DDB_0237846, anticorps F2N1.21, anticorps F2N1_21, anticorps STE24, anticorps FACE-1, anticorps FACE1, anticorps HGPS, anticorps PRO1, anticorps Ste24p, anticorps A530043O15Rik, anticorps D030046F19, anticorps Face-1, anticorps MADB, anticorps fi45a02, anticorps wu:fi45a02, anticorps zgc:55655, anticorps zinc metallopeptidase STE24, anticorps zinc metallopeptidase STE24 L homeolog, anticorps CAAX prenyl protease, anticorps Peptidase family M48 family protein, anticorps zinc metallopeptidase, STE24, anticorps zinc metallopeptidase, STE24 homolog, anticorps ZMPSTE24, anticorps zmpste24.L, anticorps zmpste24, anticorps ATSTE24, anticorps Zmpste24

Sujet: ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alias Symbols: FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1
Protein Interaction Partner: UBC, BAG3, KIAA2013, TMEM43, MRPL40, MRPS5, SYNJ2BP, ATP6V1H, HNRNPUL1, RAB10, VDAC1, UQCRFS1P1, S100A10, RAB5C, PTPN1, NDUFB7, MGST3, HNRNPF, GALNT2, DDOST, CD55, ELAVL1, MME,
Protein Size: 475

Poids moléculaire: 55 kDa

ID gène: 10269

NCBI Accession: NM_005857, NP_005848

UniProt: O75844