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MAFK anticorps (N-Term)

MAFK Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin, Mouton WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN310919
  • Antigène Voir toutes MAFK Anticorps
    MAFK (Transcription Factor MafK (MAFK))
    Épitope
    • 7
    • 6
    • 6
    • 3
    N-Term
    Reactivité
    • 27
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin, Mouton
    Hôte
    • 25
    • 2
    Lapin
    Clonalité
    • 25
    • 2
    Polyclonal
    Conjugué
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Cet anticorp MAFK est non-conjugé
    Application
    • 21
    • 16
    • 14
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    KEAGENAPVL SDDELVSMSV RELNQHLRGL TKEEVTRLKQ RRRTLKNRGY
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against MAFK. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human MAFK
    Top Product
    Discover our top product MAFK Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 156 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    MAFK (Transcription Factor MafK (MAFK))
    Autre désignation
    MAFK (MAFK Produits)
    Synonymes
    anticorps NFE2U, anticorps P18, anticorps AW061068, anticorps NF-E2, anticorps Nfe2u, anticorps MAF bZIP transcription factor K, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian), anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K, anticorps Mafk, anticorps MAFK, anticorps mafk
    Sujet
    The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2. NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, PBGD and FECH. NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG, or MafK) and p45. Both subunits are members of the activator protein-1 superfamily of bZIP proteins. Maf homodimers suppress transcription at NFE2 sites.The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD, MIM 176000) and ferrochelatase (FECH, MIM 177000). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM].
    Alias Symbols: FLJ32205, MGC71717, NFE2U, P18
    Protein Interaction Partner: NFE2L2, SMAD3, PARP1, HIF1A, UBC, SUMO2, Bach1, HDAC3, HDAC2, HDAC1, CREBBP, RELA, KAT6A, TP53, BACH2, NFE2L3, NFE2, MARS, MAFK, NFE2L1, HOXD12,
    Protein Size: 156
    Poids moléculaire
    17 kDa
    ID gène
    7975
    NCBI Accession
    NM_002360, NP_002351
    UniProt
    O60675
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