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PCDHA5 anticorps (N-Term)

PCDHA5 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN311174
  • Antigène Voir toutes PCDHA5 Anticorps
    PCDHA5 (Protocadherin alpha 5 (PCDHA5))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval
    Hôte
    • 18
    • 1
    Lapin
    Clonalité
    • 18
    • 1
    Polyclonal
    Conjugué
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PCDHA5 est non-conjugé
    Application
    • 19
    • 15
    • 14
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VYSRRGSLGS RLLLLWLLLA YWKAGSGQLH YSIPEEAKHG TFVGRIAQDL
    Homologie
    Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PCDHA5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHA5
    Top Product
    Discover our top product PCDHA5 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 936 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PCDHA5 (Protocadherin alpha 5 (PCDHA5))
    Autre désignation
    PCDHA5 (PCDHA5 Produits)
    Synonymes
    anticorps CNR6, anticorps CNRN6, anticorps CNRS6, anticorps CRNR6, anticorps PCDH-ALPHA5, anticorps Cnr6, anticorps Crnr6, anticorps rCNRv05, anticorps PCDHA5, anticorps Pcdha5, anticorps protocadherin alpha 5, anticorps protocadherin alpha-5, anticorps PCDHA5, anticorps Pcdha5, anticorps LOC100738784, anticorps LOC100847156, anticorps LOC100713870, anticorps LOC100629824
    Sujet
    The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Alias Symbols: CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5
    Protein Size: 936
    Poids moléculaire
    99 kDa
    ID gène
    56143
    NCBI Accession
    NM_018908, NP_061731
    UniProt
    Q9Y5H7
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