WDFY3 anticorps (C-Term)

N° du produit ABIN311364

Détail du produit anti-WDFY3 anticorps

Antigène: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Porc, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDFY3 est non-conjugé

Application: Western Blotting (WB)

Séquence: EKLADAVRFL GCFSDLRKIS AMNVFPSNTQ PFQRLLEEDV ISIESVSPTL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against WDFY3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human WDFY3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 795 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-WDFY3 (ABIN311364)

Yao, Jia, Feathers, Lin, Khan, Klionsky, Ferguson, Zacks: "Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration." dans: Autophagy, Vol. 12, Issue 12, pp. 2439-2450, (2016) (PubMed).

Détails sur WDFY3

Antigène: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Autre désignation: WDFY3 (WDFY3 Produits)

Synonymes: anticorps ALFY, anticorps ZFYVE25, anticorps 2610509D04Rik, anticorps AW319683, anticorps B930017C24, anticorps BWF1, anticorps Bchs, anticorps D5Ertd66e, anticorps Ggtb3, anticorps mKIAA0993, anticorps WDFY family member 4, anticorps WD repeat and FYVE domain containing 3, anticorps WD repeat and FYVE domain-containing protein 3, anticorps WDFY4, anticorps WDFY3, anticorps MGYG_03998, anticorps Wdfy3

Sujet: WDFY3 is a protein which contains WD repeats and an FYVE domain. WDFY3 might target cytosolic protein aggregates for autophagic degradation.This gene encodes a protein which contains WD repeats and an FYVE domain. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: ALFY, KIAA0993, MGC16461, ZFYVE25
Protein Interaction Partner: CEP76, TRIM39, ZBTB44, PRMT6, SUV39H1, PRMT1, SQSTM1, TRAF6, BAG3, EEF2K, ATG16L1, ATG5, ATG12, MAP1LC3A, UBC,
Protein Size: 795

Poids moléculaire: 90 kDa

ID gène: 23001

NCBI Accession: NM_178583, NP_848698

UniProt: Q8IZQ1