DPH1 anticorps (Middle Region)

N° du produit ABIN311480

Détail du produit anti-DPH1 anticorps

Antigène: DPH1 (DPH1 Homolog (DPH1))

Épitope: Middle Region

Reactivité: Humain, Souris, Lapin, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: RMQAARQEAI ATARSAKSWG LILGTLGRQG SPKILEHLES RLRALGLSFV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DPH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DPH1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 443 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DPH1

Antigène: DPH1 (DPH1 Homolog (DPH1))

Autre désignation: DPH1 (DPH1 Produits)

Synonymes: anticorps DPH1, anticorps DPH1-OVCA2, anticorps dph1-ovca2, anticorps dph2l, anticorps dph2l1, anticorps ovca1, anticorps DPH2L, anticorps DPH2L1, anticorps OVCA1, anticorps zgc:110702, anticorps 2310011M22Rik, anticorps 4930488F09Rik, anticorps AW551873, anticorps Dph2l1, anticorps Ovca1, anticorps RGD1562694, anticorps diphthamide biosynthesis 1, anticorps diphthamide biosynthesis protein 1, anticorps diphthamide biosynthesis 1 L homeolog, anticorps 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1, anticorps DPH1, anticorps NCU08503, anticorps ATEG_01183, anticorps LELG_00973, anticorps HCAG_03806, anticorps AOR_1_728014, anticorps PTRG_05729, anticorps CTRG_01524, anticorps UREG_06411, anticorps BDBG_05574, anticorps MCYG_04396, anticorps PITG_12187, anticorps MGYG_02224, anticorps LOC100284663, anticorps dph1.L, anticorps dph1, anticorps Dph1, anticorps dph-1

Sujet: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]). Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-40 AF321876.1 1-40 41-1028 BC003099.1 3-990 1029-1410 BP417755.1 78-459 1411-2188 AK090530.1 1484-2261 2189-2200 AF321876.1 2189-2200
Alias Symbols: DPH2L, DPH2L1, FLJ33211, OVCA1
Protein Interaction Partner: UBC, TFCP2, MMS19, UBD, TP63, TP73, TP53, RBM8A, HSPA5,
Protein Size: 443

Poids moléculaire: 49 kDa

ID gène: 1801

NCBI Accession: NM_001383, NP_001374

UniProt: Q9BZG8