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CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (AA 202-216) anticorps (PE)

Détails pour le produit réf. ABIN316540, Fournisseur: Connectez-vous pour afficher
Antigène
  • CD79A
  • Ig-alpha
  • Iga
  • Igalpha
  • Ly-54
  • Ly54
  • mb-1
  • IGA
  • MB-1
  • IG-alpha
Épitope
AA 202-216
49
38
23
16
15
15
10
9
5
4
3
3
3
3
2
2
1
1
1
1
1
1
1
Reactivité
Boeuf (Vache), Chien, Poulet, Cheval, Cobaye, Humain, Singe, Souris, Porc, Lapin, Rat (Rattus)
252
81
42
38
37
31
29
29
26
20
16
9
6
3
3
3
3
3
3
2
Hôte
Souris
169
112
4
1
Clonalité (Clone)
Monoclonal ()
Conjugué
PE
26
25
15
13
7
5
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS)
132
121
69
63
53
24
23
19
6
4
4
4
3
2
2
1
1
1
1
Fournisseur
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Immunogène Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1
Clone HM57
Isotype IgG1
Specificité This antibody recognises an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45 kDa protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells.
Attributs du produit Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Autre désignation CD79a (CD79A Antibody Extrait)
Sujet The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein
ID gène 973
UniProt P11912
Domaine de recherche Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Pathways
Indications d'application Flow Cytometry: use 10 μL of neat antibody to label 1x10^6 cells in 100 μL, Membranepermeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Reconstitute with 0.25 mL distilled water
Concentration 0.1 mg/mL
Buffer Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3), 1 % Bovine Serum Albumin
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store undiluted at 2-8 °C. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this productcontain a precipitate we recommend microcentrifugation before use.
Shelf life: One year from despatch.
Date de péremption 12 months
Reference: Background Jones, Cordell, Beyers et al.: "Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 12, pp. 5429-35, 1993 (PubMed).