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CSF1R anticorps (PE)

CSF1R Reactivité: Souris, Rat FACS Hôte: Rat Monoclonal 604B5 2E11 PE
N° du produit ABIN317385
  • Antigène Voir toutes CSF1R Anticorps
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Reactivité
    • 197
    • 140
    • 97
    • 17
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 224
    • 30
    • 9
    • 3
    • 2
    Rat
    Clonalité
    • 226
    • 41
    • 1
    Monoclonal
    Conjugué
    • 95
    • 27
    • 15
    • 15
    • 14
    • 11
    • 10
    • 10
    • 9
    • 9
    • 9
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CSF1R est conjugé à/à la PE
    Application
    • 175
    • 107
    • 89
    • 68
    • 50
    • 26
    • 24
    • 21
    • 12
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody recognizes the CD115 cell surface antigen, also known as the M-CSF receptor and as c-fms. This antibody has been shown to inhibit in vitro colony formation in response to M-CSF in both rats and mice.
    Réactivité croisée (Details)
    Species reactivity (tested):Mouse and Rat.
    Attributs du produit
    Synonyms: CSF-1-R, Fms proto-oncogene, c-fms, CSF1R, FMS, Macrophage colony-stimulating factor 1receptor
    Purification
    Purified IgG prepared by ion exchange chromatography
    Immunogène
    RAW 264 cells. Spleen cells from immunised Sprague Dawley rats were fused with cells of the P3-653myeloma cell line.
    Clone
    604B5 2E11
    Isotype
    IgG1
    Top Product
    Discover our top product CSF1R Anticorps primaire
  • Indications d'application
    Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1.0 mL distilled water.
    Buffer
    PBS, 0.09 % Sodium Azide, 1 % BSA
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.
    Date de péremption
    12 months
  • Antigène
    CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
    Autre désignation
    CD115 (CSF1R Produits)
    Synonymes
    anticorps AI323359, anticorps CD115, anticorps CSF-1R, anticorps Csfmr, anticorps Fim-2, anticorps Fms, anticorps M-CSF-R, anticorps M-CSFR, anticorps C-FMS, anticorps CSFR, anticorps FIM2, anticorps FMS, anticorps HDLS, anticorps PDGFRB, anticorps MGC89146, anticorps CSF-1-R, anticorps c-fms, anticorps mrfms, anticorps CSF1, anticorps M-CSF, anticorps csf1r, anticorps fms, anticorps panther, anticorps colony stimulating factor 1 receptor, anticorps macrophage colony-stimulating factor receptor, anticorps colony stimulating factor 1 receptor, a, anticorps Csf1r, anticorps CSF1R, anticorps m-csfr, anticorps csf1r, anticorps csf1ra
    Sujet
    CD115, also known as c-fms, macrophage Colony Stimulating Factor Receptor (M-CSFR), or CSF-1R, exists in immature (gp130c-fms) and mature (gp150c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of the mononuclear phagocyte lineage. CSF-1R is an integral transmembrane glycoprotein consisting of a 512 amino acid extracellular domain that includes the CSF-1 binding site, a single 25 amino acid membrane-spanning segment, and a 435 amino acid cytoplasmic portion that includes the tyrosine kinase domain. CD115 is expressed by cells of the monocytic lineage and by progenitor cells.Synonyms: CSF-1-R, CSF1R, FMS, Fms proto-oncogene, Macrophage colony-stimulating factor 1 receptor, c-fms
    ID gène
    12978
    UniProt
    P09581
    Pathways
    Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization
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