STEAP1 anticorps (N-Term)

N° du produit ABIN317568

Détail du produit anti-STEAP1 anticorps

Antigène: STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))

Épitope: AA 1-70, N-Term

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp STEAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: The antibody recognizes STEAP1.

Réactivité croisée (Details): Species reactivity (tested):Human, Rat.

Attributs du produit: Synonyms: STEAP-1, Metalloreductase STEAP1, PRSS24, Six-transmembrane epithelial antigen ofprostate 1

Purification: Protein-G affinity chromatography

Immunogène: Recombinant human STEAP1 (1-70 aa) purified from E. coli

Clone: J2D2

Isotype: IgG2b

Information d'application

Indications d'application: ELISA. Western blot (cell lysates of LNcap (30 μg) and Rat testis (30 μg) were resolved bySDS-PAGE, transferred to NC membrane and probed with anti-human STEAP1 (1: 500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRPand an ECL detection system). Immunofluorescence (1: 100 - 1: 300). Immunohistochemsitry on paraffin sections (1: 50 - 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur STEAP1

Antigène: STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))

Autre désignation: STEAP / STEAP1 (STEAP1 Produits)

Synonymes: anticorps PRSS24, anticorps STEAP, anticorps STEAP1, anticorps 2410007B19Rik, anticorps Prss24, anticorps Steap, anticorps STEAP family member 1, anticorps six transmembrane epithelial antigen of the prostate 1, anticorps STEAP1, anticorps Steap1

Sujet: Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewing's sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy. NCBI Accession No: NP_036581Synonyms: Metalloreductase STEAP1, PRSS24, STEAP-1, Six-transmembrane epithelial antigen of prostate 1

ID gène: 26872

UniProt: Q9UHE8

Pathways: Transition Metal Ion Homeostasis