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NGFR anticorps

NGFR Reactivité: Humain, Souris WB, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN318704
  • Antigène Voir toutes NGFR Anticorps
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Reactivité
    • 168
    • 61
    • 55
    • 29
    • 27
    • 26
    • 26
    • 21
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 93
    • 82
    • 4
    • 1
    Lapin
    Clonalité
    • 100
    • 80
    Polyclonal
    Conjugué
    • 93
    • 15
    • 13
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NGFR est non-conjugé
    Application
    • 109
    • 87
    • 62
    • 59
    • 49
    • 30
    • 27
    • 21
    • 21
    • 14
    • 14
    • 12
    • 9
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Specificité
    This antibody recognises CD271, a transmembrane protein of 70-75 kDa, otherwise known as Nerve Growth Factor Receptor (NGFR).
    Purification
    Purified
    Immunogène
    Recombinant human CD271
    Isotype
    IgG
    Top Product
    Discover our top product NGFR Anticorps primaire
  • Indications d'application
    Western Blot: 1g/mL, detects a band of approximately 75-80 kDa in A-20 cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0mg/mL
    Buffer
    Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Autre désignation
    CD271 / NGFR (NGFR Produits)
    Synonymes
    anticorps ngfr, anticorps wu:fb38c02, anticorps wu:fc10h01, anticorps CD271, anticorps Gp80-LNGFR, anticorps TNFRSF16, anticorps p75(NTR), anticorps p75NTR, anticorps LNGFR, anticorps RNNGFRR, anticorps Tnfrsf16, anticorps p75, anticorps NRH1b, anticorps fullback, anticorps nrh1, anticorps p75ntr, anticorps tnfrsf16, anticorps p75NGFR, anticorps nerve growth factor receptor, anticorps neurotrophin receptor associated death domain, anticorps nerve growth factor receptor S homeolog, anticorps nerve growth factor receptor (TNFR superfamily, member 16), anticorps NGFR, anticorps nradd, anticorps Ngfr, anticorps ngfr.S
    Sujet
    CD 271 is a pro-apoptotic member of the tumour necrosis factor receptor (TNFR) family and its ligands include NGF, brain derived growth neurotrophic factor (BDNF), NT3 and NT4. CD271 has been shown to interact with tropomyosin-receptor-kinase A (TrkA) forming the high-affinity NGF receptor, while CD271 can signal alone, constituting the low-affinity NGF receptor. When signalling alone, CD271 is involved in apoptosis, neurite outgrowth during development and myelination. Mutations and changes in CD271 expression have been implicated in various pathological diseases including AlzheimerSynonyms: TNFRSF16, Tumor necrosis factor receptor superfamily member 16
    ID gène
    4804
    NCBI Accession
    NP_002498
    UniProt
    P08138
    Pathways
    Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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