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FLIP anticorps (C-Term)

CFLAR Reactivité: Humain, Souris WB, IF, IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN318973
  • Antigène Voir toutes FLIP (CFLAR) Anticorps
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Épitope
    • 16
    • 15
    • 15
    • 10
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 191-209, C-Term
    Reactivité
    • 95
    • 66
    • 57
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 85
    • 15
    • 2
    Lapin
    Clonalité
    • 87
    • 15
    Polyclonal
    Conjugué
    • 54
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp FLIP est non-conjugé
    Application
    • 97
    • 39
    • 27
    • 26
    • 21
    • 20
    • 14
    • 14
    • 12
    • 9
    • 8
    • 5
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    This antibody recognises the apoptosis related protein designated FLIP (FLICE inhibitory protein).
    Purification
    Purified
    Immunogène
    A peptide corresponding to aa191 - 209 at the C-terminus of human FLIP delta/FLIPs form.
    Isotype
    IgG
    Top Product
    Discover our top product CFLAR Anticorps primaire
  • Indications d'application
    Immunohistochemistry on frozen sections: 2g/mL. Western Blot: 1: 1000, detects bands of approximately 35 kDa and 25 kDa in Jurkat celllysates.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Autre désignation
    CFLAR / Casper / I-FLICE (CFLAR Produits)
    Synonymes
    anticorps Clarp1, anticorps cflar, anticorps CFLAR, anticorps FLIP, anticorps CASH, anticorps CASP8AP1, anticorps CLARP, anticorps Casper, anticorps FLAME, anticorps FLAME-1, anticorps FLAME1, anticorps I-FLICE, anticorps MRIT, anticorps c-FLIP, anticorps c-FLIPL, anticorps c-FLIPR, anticorps c-FLIPS, anticorps 2310024N18Rik, anticorps A430105C05Rik, anticorps Cash, anticorps ENSMUSG00000072980, anticorps Flip, anticorps Gm9845, anticorps c-Flip, anticorps CASP8 and FADD-like apoptosis regulator a, anticorps CASP8 and FADD like apoptosis regulator, anticorps CASP8 and FADD like apoptosis regulator S homeolog, anticorps CASP8 and FADD-like apoptosis regulator, anticorps cflara, anticorps CFLAR, anticorps cflar, anticorps cflar.S, anticorps Cflar
    Sujet
    FLIP interacts with the adaptor protein FADD, and with Caspase-8 (FLICE) and Caspase-10 (FLICE2) to inhibit apoptosis induced by death receptors including CD95, DR3, TRAIL-R and TNFR1. FLICE inhibitory proteins were initially identified in virus and human and were accordingly designated as v-FLIPs and c-FLIPs. Four spice variants of c-FLIP have been identified and are classified as FLIP alpha, beta, delta and gamma. AHP1591 recognizes human and murine delta and gamma variants but not the alpha or beta, variants. FLIP is widely expressed in human tissues and a diverse range of cell lines.Synonyms: CASH, CASP8 and FADD-like apoptosis regulator, CASP8AP1, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP
    ID gène
    8837
    NCBI Accession
    NP_001120655
    UniProt
    O15519
    Pathways
    Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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