p53 anticorps (pSer37)
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- Antigène Voir toutes p53 (TP53) Anticorps
- p53 (TP53) (Tumor Protein P53 (TP53))
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Épitope
- pSer37
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp p53 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Specificité
- The antibody detects endogenous levels of p53 only when phosphorylated at Serine 37.
- Purification
- Affinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogène
- The antiserum was produced against synthesized phosphopeptide derived from human p53 around the phosphorylation site of Serine 37 (L-P-SP-Q-A).
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- Discover our top product TP53 Anticorps primaire
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- Indications d'application
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Western Blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody (in aliquots) at-20 °C.
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- Antigène
- p53 (TP53) (Tumor Protein P53 (TP53))
- Autre désignation
- p53 (TP53) (TP53 Produits)
- Sujet
- Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
- ID gène
- 7157
- NCBI Accession
- NP_000537
- UniProt
- P04637
- Pathways
- Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg
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