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EIF2S1 anticorps (pSer49)

EIF2S1 Reactivité: Humain, Rat, Souris WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN319276
  • Antigène Voir toutes EIF2S1 Anticorps
    EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
    Épitope
    • 19
    • 9
    • 8
    • 8
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer49
    Reactivité
    • 71
    • 42
    • 32
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 75
    • 11
    • 2
    Lapin
    Clonalité
    • 71
    • 17
    Polyclonal
    Conjugué
    • 54
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EIF2S1 est non-conjugé
    Application
    • 59
    • 37
    • 32
    • 30
    • 19
    • 13
    • 13
    • 12
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    Antibody detects endogenous levels of eIF2a only when phosphorylated at Serine 49.
    Purification
    Affinity Chromatography
    Immunogène
    Synthetic phosphopeptide derived from human eIF2a around the phosphorylation site of Serine 49 (L-L-SP-E-L).
    Top Product
    Discover our top product EIF2S1 Anticorps primaire
  • Indications d'application
    Immunofluorescence: 1/100-1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at-20 °C.
  • Antigène
    EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
    Autre désignation
    EIF2A / EIF2S1 (EIF2S1 Produits)
    Synonymes
    anticorps EIF-2, anticorps EIF-2A, anticorps EIF-2alpha, anticorps EIF2, anticorps EIF2A, anticorps Eif2s1, anticorps eif2s1l, anticorps fb36a08, anticorps wu:fb36a08, anticorps zgc:56510, anticorps 0910001O23Rik, anticorps 2410026C18Rik, anticorps 35kDa, anticorps Eif2a, anticorps eIF2alpha, anticorps eif2a, anticorps CG9946, anticorps Dmel\\CG9946, anticorps Eif2alpha, anticorps IF2A_DROME, anticorps M(1)14C, anticorps M(1)19-153, anticorps M(1)8e3-10, anticorps deIF2alpha, anticorps eIF-2, anticorps eIF-2 a, anticorps eIF-2 alpha, anticorps eIF2 alpha, anticorps eIF2-alpha, anticorps eIF2a, anticorps eiF-2alpha, anticorps elF2alpha, anticorps l(1)14Cf, anticorps l(1)19-153, anticorps eukaryotic translation initiation factor 2 subunit alpha, anticorps eukaryotic translation initiation factor 2, subunit 1 alpha a, anticorps eukaryotic translation initiation factor 2, subunit 1 alpha, anticorps eukaryotic translation initiation factor 2 alpha subunit, anticorps Eukaryotic translation initiation factor 2 subunit 1, anticorps eukaryotic translation initiation factor 2 subunit alpha L homeolog, anticorps eukaryotic translation Initiation Factor 2alpha, anticorps EIF2S1, anticorps eif2s1a, anticorps Eif2s1, anticorps eif2s1, anticorps LOC693063, anticorps CNI00230, anticorps THAPSDRAFT_105, anticorps if2a, anticorps eif2s1.L, anticorps eIF-2alpha
    Sujet
    The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD), and gamma (52 kD). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha.Synonyms: EIF2-A, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha, eIF2 alpha
    ID gène
    1965
    NCBI Accession
    NP_004085
    UniProt
    P05198
    Pathways
    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
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