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Aurora A anticorps (pThr288)

AURKA Reactivité: Humain, Souris IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN319282
  • Antigène Voir toutes Aurora A (AURKA) Anticorps
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Épitope
    • 28
    • 22
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr288
    Reactivité
    • 127
    • 74
    • 42
    • 20
    • 18
    • 14
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    Humain, Souris
    Hôte
    • 123
    • 21
    • 1
    Lapin
    Clonalité
    • 110
    • 34
    Polyclonal
    Conjugué
    • 83
    • 10
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Aurora A est non-conjugé
    Application
    • 106
    • 59
    • 37
    • 26
    • 19
    • 15
    • 12
    • 11
    • 6
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    Aurora A (phospho-Thr288) Antibody AP08036PU detects endogenous levels of Aurora A only when phosphorylated at Threonine 288.
    Purification
    Immunoaffinity Chromatography: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogène
    The antiserum was produced against synthesized phosphopeptide derived from human Aurora A around the phosphorylation site of Threonine 288 (R-T-TP-L-M).
    Top Product
    Discover our top product AURKA Anticorps primaire
  • Indications d'application
    Immunohistochemistry (1/50-1/100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at-20 °C.
  • Antigène
    Aurora A (AURKA) (Aurora Kinase A (AURKA))
    Autre désignation
    Aurora Kinase A (AURKA Produits)
    Synonymes
    anticorps AIK, anticorps ARK1, anticorps AURA, anticorps AURORA2, anticorps BTAK, anticorps PPP1R47, anticorps STK15, anticorps STK6, anticorps STK7, anticorps AIRK1, anticorps AU019385, anticorps AW539821, anticorps Ark1, anticorps Aurora-A, anticorps Ayk1, anticorps IAK, anticorps IAK1, anticorps Stk6, anticorps 87A7-9/2, anticorps Aur-A, anticorps AurA, anticorps CG3068, anticorps Dmel\\CG3068, anticorps aur-A, anticorps aurA, anticorps ck10, anticorps ck[10], anticorps l(3)87Ac, anticorps l(3)ck10, anticorps ARK-1, anticorps Eg2, anticorps aik, anticorps ark1, anticorps aur-a, anticorps aura, anticorps aurka-a, anticorps aurora2, anticorps btak, anticorps stk15, anticorps stk6, anticorps stk7, anticorps pEg2, anticorps wu:fb37c10, anticorps wu:fc02c02, anticorps zgc:100912, anticorps AURKA, anticorps aurka, anticorps aurora kinase A, anticorps aurora A, anticorps aurora kinase A L homeolog, anticorps hypothetical protein, anticorps aurora kinase A S homeolog, anticorps AURKA, anticorps Aurka, anticorps aurA, anticorps aurka.L, anticorps aurka, anticorps Aurora-A, anticorps aurka.S
    Sujet
    Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Synonyms: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
    ID gène
    6790
    NCBI Accession
    NP_003591
    UniProt
    O14965
    Pathways
    Cycle Cellulaire, Asymmetric Protein Localization
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