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CD4 anticorps (FITC)

CD4 Reactivité: Humain FACS Hôte: Souris Monoclonal RPA-T4 FITC
N° du produit ABIN319660
  • Antigène Voir toutes CD4 Anticorps
    CD4
    Reactivité
    • 379
    • 222
    • 120
    • 38
    • 24
    • 22
    • 20
    • 19
    • 15
    • 11
    • 10
    • 10
    • 8
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    • 7
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    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 361
    • 146
    • 132
    • 4
    • 2
    • 1
    • 1
    Souris
    Clonalité
    • 502
    • 138
    • 3
    Monoclonal
    Conjugué
    • 203
    • 69
    • 57
    • 51
    • 32
    • 15
    • 14
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    • 12
    • 11
    • 10
    • 9
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    • 7
    • 5
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    • 5
    • 5
    • 5
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    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CD4 est conjugé à/à la FITC
    Application
    • 510
    • 205
    • 113
    • 109
    • 86
    • 80
    • 78
    • 42
    • 39
    • 39
    • 33
    • 25
    • 17
    • 10
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    • 5
    • 4
    • 4
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    • 3
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody recognises CD4. Epitope mapping studies have shown that antibodies, produced by clone RPA-T4, recognise an epitope within domain 1, of the extracellular region, of the CD4 Molecule. Clone RPA-T4 has been reported to block gp120-CD4 interaction and inhibit syncytium formation. We recommend the use of SM1058LE for this purpose.
    Purification
    Affinity chromatography on Protein G.
    Immunogène
    Human PHA blasts. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI myeloma cell line.
    Clone
    RPA-T4
    Isotype
    IgG1
    Top Product
    Discover our top product CD4 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    CD4
    Autre désignation
    CD4 (CD4 Produits)
    Synonymes
    anticorps cd4, anticorps L3T4, anticorps Ly-4, anticorps CD4mut, anticorps W3/25, anticorps p55, anticorps CD4 molecule, anticorps carcinoembryonic antigen-related cell adhesion molecule 5, anticorps T-cell surface glycoprotein CD4, anticorps CD4 antigen, anticorps Cd4 molecule, anticorps CD4, anticorps LOC100125525, anticorps cd4, anticorps Cd4
    Sujet
    CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
    ID gène
    920
    NCBI Accession
    NP_000607
    UniProt
    P01730
    Pathways
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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