FCGR2A anticorps

N° du produit ABIN319715

Détail du produit anti-FCGR2A anticorps

Antigène: FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))

Reactivité: Humain, Singe, Chien, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FCGR2A est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This antibody recognises the CD32 antigen. Clone AT10 blocks the binding of IgG to Fc gamma R11. SM1092LE is recommended for this purpose.

Purification: Affinity Chromatography on Protein A.

Immunogène: K562 cell line. Remarks: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.

Clone: AT10

Isotype: IgG1

Information d'application

Indications d'application: Immunoprecipitation: 20 μg/mL. Flow Cytometry (20 μg/mL): Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Immunohistochemistry on Frozen Sections: 1/500-1/1000. Recommended Positive Control: Lymph node.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FCGR2A

Antigène: FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))

Autre désignation: CD32 / FcRII-A (FCGR2A Produits)

Synonymes: anticorps CD32, anticorps CD32A, anticorps CDw32, anticorps FCG2, anticorps FCGR2, anticorps FCGR2A1, anticorps FcGR, anticorps IGFR2, anticorps CD32a, anticorps Fc fragment of IgG receptor IIa, anticorps FCGR2A

Sujet: CD32 is a 40kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII). The antigen mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets.Synonyms: CDw32, FCG2, FCGR2A, FCGR2A1, Fc-gamma RII-a, Fc-gamma-RIIa, IGFR2, IgG Fc receptor II, Low affinity immunoglobulin gamma Fc region receptor II

ID gène: 2212

NCBI Accession: NP_001129691

UniProt: P12318