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ITGA2 anticorps

ITGA2 Reactivité: Humain, Singe FACS, IHC (fro) Hôte: Souris Monoclonal AK7 unconjugated
N° du produit ABIN319765
  • Antigène Voir toutes ITGA2 Anticorps
    ITGA2 (Integrin alpha 2 (ITGA2))
    Reactivité
    • 130
    • 73
    • 21
    • 12
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Singe
    Hôte
    • 82
    • 47
    • 30
    • 7
    • 7
    Souris
    Clonalité
    • 101
    • 75
    Monoclonal
    Conjugué
    • 71
    • 24
    • 19
    • 16
    • 9
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ITGA2 est non-conjugé
    Application
    • 83
    • 67
    • 44
    • 42
    • 19
    • 17
    • 16
    • 12
    • 12
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    This antibody recognises the integrin alpha 2 subunit, which is 160 kDa cell surface antigen expressed by NK cells and a small subset of T-cells. This antibody inhibits cell attachment to collagen.
    Purification
    Affinity Chromatography on Protein G.
    Immunogène
    Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line.
    Clone
    AK7
    Isotype
    IgG1
    Top Product
    Discover our top product ITGA2 Anticorps primaire
  • Indications d'application
    Flow Cytometry: 1/50-1/100, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry on Frozen Sections: 1/500-1/1000. Recommended positive control tissue: Tonsil.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ITGA2 (Integrin alpha 2 (ITGA2))
    Autre désignation
    CD49b / ITGA2 (ITGA2 Produits)
    Synonymes
    anticorps BR, anticorps CD49B, anticorps GPIa, anticorps HPA-5, anticorps VLA-2, anticorps VLAA2, anticorps DX5, anticorps integrin subunit alpha 2, anticorps integrin alpha 2, anticorps ITGA2, anticorps Itga2
    Sujet
    Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
    ID gène
    3673
    NCBI Accession
    NP_002194
    UniProt
    P17301
    Pathways
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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