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CLEC7A anticorps (PE)

CLEC7A Reactivité: Souris FACS Hôte: Rat Monoclonal 2A11 PE
N° du produit ABIN320108
  • Antigène Voir toutes CLEC7A Anticorps
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Reactivité
    • 59
    • 38
    • 6
    • 1
    Souris
    Hôte
    • 41
    • 19
    • 19
    Rat
    Clonalité
    • 42
    • 32
    Monoclonal
    Conjugué
    • 27
    • 11
    • 11
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CLEC7A est conjugé à/à la PE
    Application
    • 44
    • 39
    • 25
    • 23
    • 9
    • 8
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificité
    Recognises Murine Beta-Glucan Receptor (Dectin-1). This antibody inhibits the binding of zymosan to macrophages via the beta-glucan receptor. The low endotoxin version SM2025LE is recommended for Functional Studies.
    Purification
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    Immunogène
    Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1. Spleen cells from immunised Fischer rats were fused with cells of the rat Y3 myeloma cell line2
    Clone
    2A11
    Isotype
    IgG2b
    Top Product
    Discover our top product CLEC7A Anticorps primaire
  • Indications d'application
    Flow Cytometry (Neat -1/10): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1 mL distilled water
    Buffer
    PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA and 5 % sucrose as stabilizers.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    This product is photosensitive and should be protected from light
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Antigène
    CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
    Autre désignation
    CLEC7A / Dectin-1 (CLEC7A Produits)
    Synonymes
    anticorps CLEC7A, anticorps BGR, anticorps Clecsf12, anticorps beta-GR, anticorps CANDF4, anticorps CLECSF12, anticorps DECTIN1, anticorps Clec7b, anticorps RGD1565140, anticorps C-type lectin domain containing 7A, anticorps C-type lectin domain family 7, member a, anticorps CLEC7A, anticorps Clec7a
    Sujet
    Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk.Synonyms: BGR, Beta-glucan receptor, C-type lectin domain family 7 member A, C-type lectin superfamily member 12, CLECSF12, DC-associated C-type lectin 1, DECTIN1, Dendritic cell-associated C-type lectin 1
    ID gène
    56644
    NCBI Accession
    NP_064392
    UniProt
    Q6QLQ4
    Pathways
    Activation of Innate immune Response
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