anti-Usp11 anticorps

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	Antigène:	Usp11
	Clonalité:	Polyclonal
	Application:	Immunohistochemistry (IHC)
	Reactivité:	Mouse (Murine)
	Hôte:	Rabbit
	Quantité:	25 ug (0.25 mg/ml)
	Prix:	806,49 $ (Plus frais de livraison $25 et TVA, Invoice in EUR)
	Numéro du produit:	ABIN334288
	Disponibilité:	Envoi sous 5 à 10 jours ouvrables

Antigène	Usp11
ID gène	236733
Immunogène	Partial peptide of Mouse Usp11
Reactivité	Mouse (Murine)
Clonalité	Polyclonal
Format	Affinity Purified
Description	Usp11 (ubiquitin specific peptidase 11) possesses Cys box, His box, Asp and KRF domains, which are highly conserved in many ubiquitin-specific proteases. Usp11 is a ubiquitous protein in various tissues and is primarily localized in the nucleus of non-dividing cells. Usp11 binds specifically to RanBPM which is a RanGTP-binding protein required for correct nucleation of microtubles and inhibits its ubiquitination and degradation. It has been also shown that Usp11 is involved in regulation of the TNFalpha-induced IKKalpha --> p53 signaling pathway and that Usp11 functions in stabilizing HPV-16E7 by reducing ubiquitination and attenuating E7 degradation. Alternate Names: MGC6649, KIAA4085, mKIAA4085, 6230415D12Rik, Usp11 ubiquitin specific peptidase 11.
Hôte	Rabbit

Application	Immunohistochemistry (IHC)
Indications d'application	IHC: 5.0-10 ug/mL (Paraffin embedded Sections)
Concentration	0.25 mg/ml
Buffer	PBS [containing 2 % Block Ace as a stabilizer, 0.1 %Proclin as a bacteriostat]
Stock	Store below -20
Domaine de recherche	Enzymes
Restrictions	For Research Use only