AMBRA1 anticorps (N-Term)

N° du produit ABIN347117

Détail du produit anti-AMBRA1 anticorps

Antigène: AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMBRA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Specificité: Reacts with mouse 120 kDa Ambra1 protein

Réactivité croisée: Rat (Rattus)

Réactivité croisée (Details): Cross reacts with human and rat protein.

Purification: Antiserum

Immunogène: Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Références pour anticorps anti-AMBRA1 (ABIN347117)

Armstrong, Corazzari, Martin, Pagliarini, Falasca, Hill, Ellis, Al Sabah, Redfern, Fimia, Piacentini, Lovat: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).

Di Bartolomeo, Corazzari, Nazio, Oliverio, Lisi, Antonioli, Pagliarini, Matteoni, Fuoco, Giunta, DAmelio, Nardacci, Romagnoli, Piacentini, Cecconi, Fimia: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." dans: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, (2010) (PubMed).

Détails sur AMBRA1

Antigène: AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))

Autre désignation: Activating Molecule in BECN1-Regulated Autophagy Protein 1 (Ambra1) (AMBRA1 Produits)

Sujet: Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation

ID gène: 55626

UniProt: Q9C0C7

Pathways: Autophagy