ACCN1 anticorps (AA 470-503)

N° du produit ABIN350042

Détail du produit anti-ACCN1 anticorps

Antigène: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Épitope: AA 470-503

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACCN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for ASIC2.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from AA 470-503 of human ASIC2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur ACCN1

Antigène: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Autre désignation: ASIC2 (ACCN1 Produits)

Synonymes: anticorps ACCN, anticorps ACCN1, anticorps ASIC2a, anticorps BNC1, anticorps BNaC1, anticorps MDEG, anticorps hBNaC1, anticorps ACIC2, anticorps Accn1, anticorps BNaC1a, anticorps Mdeg, anticorps BNC1k, anticorps MDEG1, anticorps MDEG2, anticorps accn1, anticorps zASIC2, anticorps acid sensing ion channel subunit 2, anticorps acid-sensing (proton-gated) ion channel 2, anticorps ASIC2, anticorps Asic2, anticorps asic2

Sujet: FUNCTION: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins. Interacts with STOM. Interacts with PRKCABP and ACCN3. SUBCELLULAR LOCATION: Cell membrane, Multi-pass membrane protein. Note: Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes.,ACCN Channels,Amiloride-sensitive brain sodium channel, acid-sensing ion channel 2, ASIC2, brain sodium channel 1, BNaC1, BNC1, mammalian degenerin homolog, ACCN, BNAC1, MDEG

UniProt: Q16515

Pathways: Sensory Perception of Sound