Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ASIC1 anticorps (AA 480-528)

ACCN2 Reactivité: Souris, Humain, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN350045
  • Antigène Voir toutes ASIC1 (ACCN2) Anticorps
    ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
    Épitope
    • 15
    • 14
    • 13
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 480-528
    Reactivité
    • 75
    • 68
    • 41
    • 12
    • 11
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Souris, Humain, Rat
    Hôte
    • 74
    • 16
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 77
    • 16
    Polyclonal
    Conjugué
    • 30
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ASIC1 est non-conjugé
    Application
    • 87
    • 36
    • 26
    • 17
    • 17
    • 15
    • 13
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Specific for AISC1.
    Immunogène
    A synthetic peptide from aa region 480-528 of human ASIC1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
    Isotype
    IgG
    Top Product
    Discover our top product ACCN2 Anticorps primaire
  • Indications d'application
    A concentration of 10-50 µg/ml is recommended.
    The optimal dilution should be determined by the end user.
    Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
    Autre désignation
    ASIC1 (ACCN2 Produits)
    Synonymes
    anticorps ACCN2, anticorps ASIC, anticorps BNaC2, anticorps Accn2, anticorps ASIC1, anticorps AI843610, anticorps ASIC1a, anticorps B530003N02Rik, anticorps acid sensing ion channel subunit 1, anticorps acid-sensing (proton-gated) ion channel 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1, anticorps ASIC1, anticorps Asic1, anticorps asic1, anticorps SMARCD1
    Sujet
    This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobictransmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit, however, its function as an ion channel remains unknown.
    Function: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Ca(2+), Li(+) and K(+).
    Subcellular location: Cell membrane, Multi-pass membrane protein. Note: Localizes in synaptosomes at dendritic synapses of neurons.
    Tissue specificity: Expressed in dorsal root ganglia (DRG) and sciatic nerve (at protein level). Widely distributed throughout the brain. Expressed inolfactory bulb, neo and allocortical regions, dentate granule cells, pyramidal cells of CA1-CA3 subfields of the hippocampal formation, habenula, basolateral amygdaloid nuclei, and in the Purkinje and granule cells of the cerebellum. Diffusely detected over most other regions of the basal ganglia, including thalamic nuclei, substantia nigra, striatum and globus pallidus, hypothalamus, midbrain, pons, medulla and choroid plexus. Isoform 3 is expressed only in dorsal root ganglion  while isoform 1 is expressed in DRG, spinal chord, trigeminal ganglia and the trigeminal mesencephalic nucleus. Also known as: Acid-sensing ion channel 1, ASIC1, Brain sodium channel 2, BNaC2, ACCN2.
Vous êtes ici:
Support technique