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ATG12 anticorps (Autophagy Related 12) (AA 20-70)

Détail du produit anti-ATG12 anticorps No. ABIN350093, Fournisseur: Connectez-vous pour afficher
Antigène
  • APG12
  • APG12L
  • FBR93
  • HAPG12
  • 4931423H11Rik
  • A330058M13Rik
  • Apg12l
  • Atg12l
  • ATG12 autophagy related 12 homolog (S. cerevisiae)
  • autophagy related 12
  • similar to S. cerevisiae ATG12 (YBR217W) which nucleates preautophagosome formation as a conjugate with Atg5
  • ATG12
  • Atg12
Épitope
AA 20-70
60
22
15
14
14
14
6
5
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Reactivité
Mouche des fruits (Drosophila melanogaster)
204
74
55
6
4
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Hôte
Lapin
186
27
4
1
Clonalité
Polyclonal
Conjugué
Cet anticorp ATG12 est non-conjugé
10
10
10
9
9
9
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
165
96
83
83
47
20
13
10
4
4
1
1
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Immunogène A synthetic peptide from aa region 20-70 of drosophila ATG12 conjugated to blue carrier protein has been used as the antigen.
Specificité Specific for ATG12.
Purification Whole serum
Autre désignation ATG12 (ATG12 Antibody Extrait)
Sujet Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved inautophagy. Following conjugation to ATG5, the conjugate participates in the formation of autophagosome. Also known as: APG12-like, HAPG12, APG12, ATG12autophagy related 12 homolog.
Indications d'application Use at a dilution of 1:300 to 1: 2000.
The optimal dilution should be determined by the end user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Conseil sur la manipulation Avoid freeze and thaw cycles.
Stock 4 °C/-20 °C
Stockage commentaire Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Date de péremption 12 months
Background publications Scott, Schuldiner, Neufeld: "Role and regulation of starvation-induced autophagy in the Drosophila fat body." dans: Developmental cell, Vol. 7, Issue 2, pp. 167-78, 2004 (PubMed).

Adams, Celniker, Holt, Evans, Gocayne, Amanatides, Scherer, Li, Hoskins, Galle, George, Lewis, Richards, Ashburner, Henderson, Sutton, Wortman, Yandell, Zhang, Chen, Brandon, Rogers, Blazej, Champe, Pfeiffer, Wan, Doyle, Baxter, Helt, Nelson, Gabor, Abril: "The genome sequence of Drosophila melanogaster." dans: Science (New York, N.Y.), Vol. 287, Issue 5461, pp. 2185-95, 2000 (PubMed).