CACNA1E anticorps

N° du produit ABIN350141

Détail du produit anti-CACNA1E anticorps

Antigène: CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA1E est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for CACNA1E.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from human CACNA1E (Cav2.3) conjugated to blue carrier protein was used as the antigen.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur CACNA1E

Antigène: CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))

Autre désignation: CACNA1E (CACNA1E Produits)

Synonymes: anticorps caV2.3, anticorps CACNA1E, anticorps BII, anticorps CACH6, anticorps CACNL1A6, anticorps Cav2.3, anticorps A430040I15, anticorps Cach6, anticorps Cacnl1a6, anticorps Cchra1, anticorps alpha1E, anticorps CACHA1E, anticorps calcium voltage-gated channel subunit alpha1 E, anticorps calcium channel, voltage-dependent, R type, alpha 1E subunit, anticorps CACNA1E, anticorps cacna1e, anticorps Cacna1e

Sujet: Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels contaning alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing. Subcellular location: Membrane, Multi-pass membrane protein. Tissue specificity: Expressed in neuronal tissues and in kidney.,Alpha Subunit,Voltage-dependent R-type calcium channel subunit alpha-1E, Voltage-gated calcium channel subunit alpha Cav2.3, Calcium channel, L type, alpha-1 polypeptide, Brain calcium channel II, CACH6, CACNL1A6

UniProt: Q15878

Pathways: Carbohydrate Homeostasis