c-FOS anticorps

N° du produit ABIN350206

Détail du produit anti-c-FOS anticorps

Antigène: c-FOS (c-Fos) (c-Fos)

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp c-FOS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for cFos.

Réactivité croisée: Humain, Marmoset, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from human c Fos protein conjugated to blue carrier protein has been used as the antigen.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur c-FOS

Antigène: c-FOS (c-Fos) (c-Fos)

Autre désignation: c Fos (c-Fos Produits)

Synonymes: anticorps AP-1, anticorps C-FOS, anticorps p55, anticorps c-fos, anticorps D12Rfj1, anticorps cFos, anticorps cFOS, anticorps fos, anticorps Fos proto-oncogene, AP-1 transcription factor subunit, anticorps FBJ osteosarcoma oncogene, anticorps proto-oncogene c-Fos-like, anticorps FOS, anticorps Fos, anticorps LOC101078177

Sujet: FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. SUBUNIT: Heterodimer. Interacts with DSIPI, this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB SUBCELLULAR LOCATION: Nucleus. INDUCTION: C-fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury. SIMILARITY: Belongs to the bZIP family. Fos subfamily SIMILARITY: Contains 1 bZIP domain,Nuclear Signaling,Proto-oncogene protein cFOS

UniProt: P01100

Pathways: S100 Proteins