CHMP3 anticorps (N-Term)
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- Antigène Voir toutes CHMP3 Anticorps
- CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))
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Épitope
- N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CHMP3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificité
- Specific for CHMP3.
- Réactivité croisée
- Humain, Souris, Rat
- Réactivité croisée (Details)
- Other species not yet tested.
- Purification
- IgG
- Immunogène
- A synthetic peptide from the n-terminal of human VPS24 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
- Isotype
- IgG
- Top Product
- Discover our top product CHMP3 Anticorps primaire
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- Indications d'application
- IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- Conseil sur la manipulation
- Avoid freeze and thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))
- Autre désignation
- VPS24 (CHMP3 Produits)
- Sujet
- FUNCTION: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. Required for sorting/trafficking of EGF receptor. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins. SUBCELLULAR LOCATION: Cytoplasm, cytosol. Membrane, Lipid-anchor. TISSUE SPECIFICITY: Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,Vesicle Protein Sorting,Chromatin-modifying protein 3, Vacuolar protein-sorting-associated protein 24, hVps24, Neuroendocrine differentiation factor, Charged multivesicular body protein 3, NEDF
- UniProt
- Q9Y3E7
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