Dynactin 1 anticorps (AA 120-170)

N° du produit ABIN350280

Détail du produit anti-Dynactin 1 anticorps

Antigène: Dynactin 1 (DCTN1)

Épitope: AA 120-170

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynactin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for DCTN1.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from AA 120-170 of human DCTN1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and moue.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur Dynactin 1

Antigène: Dynactin 1 (DCTN1)

Autre désignation: DCTN1 (DCTN1 Produits)

Synonymes: anticorps DAP-150, anticorps DP-150, anticorps P135, anticorps Chip150, anticorps DCTN1, anticorps DKFZp469C1813, anticorps AL022633, anticorps Glued, anticorps p150, anticorps p150, anticorps CG9206, anticorps DYNA_DROME, anticorps Dmel\\CG9206, anticorps FCP-D, anticorps Glu, anticorps P150, anticorps P150[Glued], anticorps p150/Glued, anticorps p150/glued, anticorps p150[Glued], anticorps p150[glued], anticorps t1, anticorps Dynactin-1, anticorps glued, anticorps dynactin subunit 1, anticorps dynactin 1, anticorps Dynactin 1, p150 subunit, anticorps dynactin subunit 1 L homeolog, anticorps DCTN1, anticorps Dctn1, anticorps DCTN1-p150, anticorps dctn1.L

Sujet: FUNCTION: Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. SUBUNIT: Large macromolecular complex of at least 10 components, p150(glued) binds directly to microtubules and to cytoplasmic dynein. Interacts with the C-terminus of MAPRE1, MAPRE2 and MAPRE3. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton. TISSUE SPECIFICITY: Brain. DISEASE: Defects in DCTN1 are the cause of progressive lower motor neuron disease. PLMND is a progressive dominant disease that has no sensory symptoms.,Signal Transduction,DAP-150, DP-150, p150-glued,p135, Dynactin subunit 1, 150 kDa dynein-associated polypeptide

UniProt: Q14203

Pathways: M Phase, ER-Nucleus Signaling