Desmin anticorps (C-Term)

N° du produit ABIN350288

Détail du produit anti-Desmin anticorps

Antigène: Desmin (DES)

Épitope: C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for Desmin.

Réactivité croisée: Humain, Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from c-terminal region of mouse Desmin conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in human and rat.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 1000 μL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: Desmin (DES Produits)

Synonymes: anticorps DES, anticorps des-b, anticorps MGC80853, anticorps des, anticorps csm1, anticorps csm2, anticorps desm, anticorps cmd1i, anticorps MGC75911, anticorps LOC100220724, anticorps desmin, anticorps cb290, anticorps fb59a12, anticorps wu:fb59a12, anticorps zgc:109859, anticorps CSM1, anticorps CSM2, anticorps LGMD2R, anticorps wu:fc11d08, anticorps zgc:154009, anticorps des-a, anticorps MGC52614, anticorps desmin, anticorps desmin, gene 1 L homeolog, anticorps desmin, gene 1, anticorps desmin a, anticorps desmin b, anticorps desmin, gene 1 S homeolog, anticorps desmin, gene 2 S homeolog, anticorps DES, anticorps des.1.L, anticorps des.1, anticorps des, anticorps desma, anticorps Des, anticorps desmb, anticorps des.1.S, anticorps des.2.S

Sujet: Function: Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. Defects in DES are the cause of desmin-related cardio-skeletal myopathy (CSM), also known as desmin-related myopathy (DRM). CSM is characterized by skeletal muscle weakness associated with cardiac conduction blocks, arrhythmias, restrictive heart failure, and by intracytoplasmic accumulation of desmin-reactive deposits in cardiac and skeletal muscle cells. A desmin-related myopathy can have a distal onset, it is then known as hereditary distal myopathy (HDM). Defects in DES are the cause of neurogenic scapuloperoneal syndrome Kaeser type (Kaeser syndrome). Subcellular location: Cytoplasm.,Stem Cells,Des

UniProt: P31001