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Kir2.2 anticorps (Cytoplasmic Domain)

KCNJ12 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN350388
  • Antigène Voir toutes Kir2.2 (KCNJ12) Anticorps
    Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))
    Épitope
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cytoplasmic Domain
    Reactivité
    • 25
    • 12
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 27
    • 1
    Lapin
    Clonalité
    • 27
    • 1
    Polyclonal
    Conjugué
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    Cet anticorp Kir2.2 est non-conjugé
    Application
    • 22
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Specific for KCNJ12.
     Réactivité croisée
    Humain
    Réactivité croisée (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogène
    A synthetic peptide from the cytoplasmic domain of human KCNJ12 (KCNJN1, Kir2.2, IRK2) conjugated to an immunogenic carrier protein was used as the antigen.
    Isotype
    IgG
    Top Product
    Discover our top product KCNJ12 Anticorps primaire
  • Indications d'application
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))
    Autre désignation
    KCNJ12 (KCNJ12 Produits)
    Synonymes
    anticorps IRK-2, anticorps IRK2, anticorps KCNJN1, anticorps Kir2.2, anticorps Kir2.2v, anticorps hIRK, anticorps hIRK1, anticorps hkir2.2x, anticorps kcnj12x, anticorps Kir2.1, anticorps IRK, anticorps KIR2.2, anticorps MB-IRK2, anticorps potassium voltage-gated channel subfamily J member 12, anticorps ATP-sensitive inward rectifier potassium channel 12, anticorps potassium inwardly-rectifying channel, subfamily J, member 12, anticorps KCNJ12, anticorps LOC746628, anticorps Kcnj12
    Sujet
    FUNCTION: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Tissue specificity: Heart, brain, placenta, lung, skeletal muscle, and kidney. Diffusely distributed throughout the brain. Subcellular location: Membrane, Multi-pass membrane protein.,Inward Rectifier,ATP-sensitive inward rectifier potassium channel 12, Potassium channel, inwardly rectifying subfamily J member 12, Inward rectifier K(+) channel Kir2.2, Kir2.2v, IRK2, KCNJN1
    UniProt
    Q14500
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