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OLIG2 anticorps (AA 80-130)

OLIG2 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN350657
  • Antigène Voir toutes OLIG2 Anticorps
    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
    Épitope
    • 16
    • 9
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-130
    Reactivité
    • 64
    • 42
    • 41
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 72
    • 11
    • 1
    Lapin
    Clonalité
    • 63
    • 21
    Polyclonal
    Conjugué
    • 45
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp OLIG2 est non-conjugé
    Application
    • 51
    • 38
    • 21
    • 14
    • 13
    • 13
    • 13
    • 11
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Specific for OLIG2.
    Immunogène
    A synthetic peptide from aa region 80-130 of human OLIG2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
    Isotype
    IgG
    Top Product
    Discover our top product OLIG2 Anticorps primaire
  • Indications d'application
    A concentration of 10-50 µg/ml is recommended.
    The optimal concentration should be determined by the end user.
    Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
    Autre désignation
    OLIG2 (OLIG2 Produits)
    Synonymes
    anticorps olig3.2, anticorps MGC89336, anticorps OLIG2, anticorps BHLHB1, anticorps OLIGO2, anticorps PRKCBP2, anticorps RACK17, anticorps bHLHe19, anticorps wu:fc64g09, anticorps AI604895, anticorps Bhlhb1, anticorps Olg-2, anticorps Oligo2, anticorps RK17, anticorps oligodendrocyte transcription factor 4, anticorps oligodendrocyte transcription factor 2, anticorps oligodendrocyte lineage transcription factor 2, anticorps olig4, anticorps OLIG2, anticorps Olig2, anticorps olig2
    Sujet
    Function: Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.
    Subcellular location: Nucleus. Cytoplasm
    Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. Involvement in disease: A chromosomal aberration involving OLIG2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(14,21)(q11.2,q22) with TCRA. Also known as: Basic helix loop helix protein class B 1, BHLHB1, olig2, OLIGO2, Oligodendrocyte specific bHLH transcription factor 2, Oligodendrocyte transcription factor 2, PRKCBP2, Protein kinase C binding protein 2, Protein kinase C binding protein RACK17, RACK17.
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