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Pro BDNF anticorps

proBDNF Reactivité: Rat IHC, WB Hôte: Mouton Polyclonal unconjugated
N° du produit ABIN350770
  • Antigène Tous les produits Pro BDNF (proBDNF)
    Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))
    Reactivité
    • 5
    • 4
    • 2
    Rat
    Hôte
    • 3
    • 2
    • 1
    Mouton
    Clonalité
    • 4
    • 2
    Polyclonal
    Conjugué
    • 5
    • 1
    Cet anticorp Pro BDNF est non-conjugé
    Application
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Specificité
    Specific for proBDNF.
     Réactivité croisée
    Souris, Rat
    Réactivité croisée (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogène
    A synthetic peptide from rat proBDNF conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and zebrafish and shares 96% identity with human sequence.
    Isotype
    IgG
  • Indications d'application
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Pro BDNF (proBDNF) (Pro-Brain-Derived Neurotrophic Factor (proBDNF))
    Abstract
    proBDNF Produits
    Sujet
    FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted.,BDNF,Brain-derived neurotrophic factor precursor, proBDNF, pro BDNF
    UniProt
    P23363
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