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RHOB anticorps

RHOB Reactivité: Humain, Souris, Rat WB, IHC Hôte: Mouton Polyclonal unconjugated
N° du produit ABIN350804
  • Antigène Voir toutes RHOB Anticorps
    RHOB (Ras Homolog Gene Family, Member B (RHOB))
    Reactivité
    • 44
    • 18
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 44
    • 1
    Mouton
    Clonalité
    • 44
    • 1
    Polyclonal
    Conjugué
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RHOB est non-conjugé
    Application
    • 18
    • 13
    • 13
    • 13
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Specific for RhOB.
     Réactivité croisée
    Humain, Souris, Rat
    Réactivité croisée (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogène
    A synthetic peptide as a part of human, rat, mouse Rho-related GTP-binding protein RhoB (ARH6, ARHB, H6) conjugated to an immunogenic carrier protein was used as the immunogen.
    Isotype
    IgG
    Top Product
    Discover our top product RHOB Anticorps primaire
  • Indications d'application
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    RHOB (Ras Homolog Gene Family, Member B (RHOB))
    Autre désignation
    RhoB (RHOB Produits)
    Synonymes
    anticorps ARH6, anticorps ARHB, anticorps MST081, anticorps MSTP081, anticorps RHOH6, anticorps AA017882, anticorps Arh6, anticorps Arhb, anticorps RHO, anticorps arha, anticorps rhoa, anticorps wu:fj42e08, anticorps zgc:92206, anticorps rhob, anticorps xrhob, anticorps ras homolog family member B, anticorps ras homolog gene family, member Ab, anticorps ras homolog family member B S homeolog, anticorps RHOB, anticorps Rhob, anticorps rhoab, anticorps rhob.S
    Sujet
    FUNCTION: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. SUBUNIT: Binds ROCK1 and ROCK2. Also binds PKN1/PRK1. Interacts with ARHGEF3 and AKAP13. Interacts with RTKN. SUBCELLULAR LOCATION: Late endosome membrane, Lipid-anchor. Cell membrane, Lipid-anchor. Nucleus. Note: Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. INDUCTION: By UV irradiation, N-methyl-N-nitrosourea, cisplatin, cyclohexamide and serum stimulation.,Rho Family,H6, ARH6, ARHB, RHOH6, MST081, MSTP081
    UniProt
    P62745
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