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TRKB anticorps (Extracellular Domain)

NTRK2 Reactivité: Souris WB, IHC Hôte: Mouton Polyclonal unconjugated
N° du produit ABIN351075
  • Antigène Voir toutes TRKB (NTRK2) Anticorps
    TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
    Épitope
    • 16
    • 15
    • 12
    • 12
    • 10
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 400-450, Extracellular Domain
    Reactivité
    • 135
    • 92
    • 86
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 140
    • 9
    • 3
    • 1
    • 1
    Mouton
    Clonalité
    • 131
    • 23
    Polyclonal
    Conjugué
    • 85
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp TRKB est non-conjugé
    Application
    • 110
    • 54
    • 50
    • 21
    • 19
    • 18
    • 15
    • 14
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Specific for TrkB.
     Réactivité croisée
    Souris, Rat
    Réactivité croisée (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogène
    A synthetic peptide from AA 400-450 of the extracellular domain of mouse TrkB conjugated to blue carrier protein was used as the antigen.
    Isotype
    IgG
    Top Product
    Discover our top product NTRK2 Anticorps primaire
  • Indications d'application
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))
    Autre désignation
    TrkB (NTRK2 Produits)
    Synonymes
    anticorps trkb, anticorps trkb-b, anticorps xtrkb, anticorps si:ch211-220b11.1, anticorps trkB2, anticorps NTRK2, anticorps ntrk2, anticorps gp145-trkb, anticorps TRKB, anticorps GP145-TrkB, anticorps trk-B, anticorps AI848316, anticorps C030027L06Rik, anticorps Tkrb, anticorps trkB, anticorps RATTRKB1, anticorps TRKB1, anticorps Trk-B, anticorps TrkB, anticorps neurotrophic receptor tyrosine kinase 2, anticorps neurotrophic receptor tyrosine kinase 2 L homeolog, anticorps neurotrophic tyrosine kinase, receptor, type 2b, anticorps neurotrophic receptor tyrosine kinase 2 S homeolog, anticorps neurotrophic tyrosine kinase, receptor, type 2, anticorps NTRK2, anticorps ntrk2.L, anticorps ntrk2b, anticorps ntrk2.S, anticorps ntrk2, anticorps Ntrk2
    Sujet
    FUNCTION: Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1. CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. Binds SH2B2. Interacts with SQSTM1 and ARMS. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.,Neurotrophic Receptors,Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B, BDNF/NT-3 growth factors receptor
    UniProt
    Q63604
    Pathways
    Signalisation RTK, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport
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