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Tyrosinase-Related Protein 1 anticorps (4th Cytoplasmic Loop)

TYRP1 Reactivité: Drosophila melanogaster WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN351091
  • Antigène Voir toutes Tyrosinase-Related Protein 1 (TYRP1) Anticorps
    Tyrosinase-Related Protein 1 (TYRP1)
    Épitope
    • 15
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    4th Cytoplasmic Loop
    Reactivité
    • 105
    • 57
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    Drosophila melanogaster
    Hôte
    • 78
    • 30
    • 1
    • 1
    Lapin
    Clonalité
    • 54
    • 54
    • 2
    Polyclonal
    Conjugué
    • 53
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Tyrosinase-Related Protein 1 est non-conjugé
    Application
    • 64
    • 39
    • 37
    • 31
    • 25
    • 22
    • 14
    • 14
    • 13
    • 5
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Specific for TRP.
     Réactivité croisée
    Drosophila melanogaster
    Réactivité croisée (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogène
    A synthetic peptide from 4th cytoplasmic loop of drosophila TRP (Transient receptor potential protein) conjugated to an immunogenic carrier protein was used as the immunogen.
    Isotype
    IgG
    Top Product
    Discover our top product TYRP1 Anticorps primaire
  • Indications d'application
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Tyrosinase-Related Protein 1 (TYRP1)
    Autre désignation
    TRP (TYRP1 Produits)
    Synonymes
    anticorps CAS2, anticorps CATB, anticorps GP75, anticorps OCA3, anticorps TRP, anticorps TRP1, anticorps TYRP, anticorps b-PROTEIN, anticorps LOC397853, anticorps Trypsin, anticorps hm:zeh0659, anticorps tyrp1, anticorps zgc:100893, anticorps B, anticorps TYRP1, anticorps tyrp-1, anticorps TRP-1, anticorps Tyrp, anticorps b, anticorps brown, anticorps isa, anticorps tyrosinase related protein 1, anticorps protease, serine 1 L homeolog, anticorps tyrosinase-related protein 1b, anticorps tyrosinase-related protein 1, anticorps tyrosinase-related protein 1 L homeolog, anticorps tyrosinase-related protein 1a, anticorps TYRP1, anticorps prss1.L, anticorps tyrp1b, anticorps Tyrp1, anticorps tyrp1.L, anticorps tyrp1, anticorps LOC100136490, anticorps tyrp-1, anticorps tyrp1a
    Sujet
    FUNCTION: A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Ca(2+) influx may then feed back and inhibit PLC, thereby facilitating phosphatidylinositol 4,5 bisphosphate (PIP2) recycling. Trp and trpl act together in the light response, though it is unclear whether as heteromultimers or as distinct units, and are activated by fatty acids and metabolic stress. Also required for olfactory adaptation and may be involved in olfactory system development. SUBUNIT: The C-terminus interacts with a PDZ domain of inaD to form the core of the inaD signaling complex. Other members of the complex include norpA (PLC), inaC (PKC), and possibly trpl, ninaC, FKBP59, calmodulin and rhodopsin. Forms homomultimers and heteromultimers with trpl. Interaction with trpl is mediated in part by the N-terminal region and the transmembrane domains. Also interacts, though to a lower extent, with trp-gamma. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. Note: Localized on plasma membrane loops found at the base of the rhabdomere, in close proximity to the calcium stores. TISSUE SPECIFICITY: Expressed predominantly in the rhabdomeres of photoreceptor cells. Expressed in the third antennal segment and in the olfactory segment at approximately 70 hours after puparium formation during antennal development.,Drosophila TRP,Transient receptor potential cation channel protein
    UniProt
    P19334
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