TRPA1 anticorps (AA 1050-1120)

N° du produit ABIN351107

Détail du produit anti-TRPA1 anticorps

Antigène: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Épitope: AA 1050-1120

Reactivité: Rat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificité: Specific for TRPA1.

Réactivité croisée: Souris, Rat

Réactivité croisée (Details): Other species not yet tested.

Purification: IgG

Immunogène: A synthetic peptide from AA 1050-1120 of rat TRPA1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in mouse.

Isotype: IgG

Information d'application

Indications d'application: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

Conseil sur la manipulation: Avoid freeze and thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TRPA1 (ABIN351107)

Cho, Lee, Choi, Choi, Lim, Kim, Kim, Jung, Hwang: "GPR171 Activation Modulates Nociceptor Functions, Alleviating Pathologic Pain." dans: Biomedicines, Vol. 9, Issue 3, (2021) (PubMed).

Nagy, Lynn, Senecal, Stecina: "Connexin36 Expression in Primary Afferent Neurons in Relation to the Axon Reflex and Modality Coding of Somatic Sensation." dans: Neuroscience, Vol. 383, pp. 216-234, (2018) (PubMed).

Détails sur TRPA1

Antigène: TRPA1 (Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1))

Autre désignation: TRPA1 (TRPA1 Produits)

Synonymes: anticorps trpa1, anticorps ANKTM1, anticorps Anktm1, anticorps CG5751, anticorps CG5761, anticorps CT18073, anticorps DmTRPA1, anticorps Dmel\\CG5751, anticorps TRPA, anticorps TRPA1, anticorps TrpA, anticorps dANKTM1, anticorps dTRPA, anticorps dTRPA1, anticorps dTrpA, anticorps dTrpA1, anticorps dtrpA1, anticorps trpA1, anticorps GLEAN_02449, anticorps FEPS, anticorps transient receptor potential cation channel, subfamily A, member 1a, anticorps Transient receptor potential cation channel A1, anticorps transient receptor potential cation channel subfamily A member 1, anticorps transient receptor potential A1, anticorps tryptophan synthase subunit alpha 1, anticorps transient receptor potential cation channel, subfamily A, member 1, anticorps TRPA cation channel homolog, anticorps trpa1a, anticorps TrpA1, anticorps TRPA1, anticorps LOC658860, anticorps LOC694623, anticorps trpA1, anticorps trpa1, anticorps Trpa1, anticorps trpa-1

Sujet: The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined, however, studies indicate the function may involve a role in signal transduction and growth control. TISSUE SPECIFICITY: Expressed in inner ear. In inner ear, it is found in the distal half of stereocilia, along the length of the kinocilium and at high level in the pericuticular zone (at protein level). Specifically expressed in a subset of nociceptive neurons. Expressed in the same neurons that TRPV1. In contrast, it is not expressed in neurons expressing TRPM8. Expressed in the superior cervical ganglion. DEVELOPMENTAL STAGE: During utricle development, it is first expressed at E15 and E16 and peaks at E17. It drops at E18 but increases again at E19, possibly corresponding to a second wave of hair cells that are generated at E15. Inhibited by ruthenium red, a potent blocker of TRPV channels.,Mammalian TRPA,Transient receptor potential cation channel subfamily A member 1, ankyrin-like with transmembrane domains protein 1, transformation sensitive protein p120, ANKTM1

UniProt: Q6RI86