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TRPM7 anticorps (4th Cytoplasmic Loop)

TRPM7 Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN351218
  • Antigène Voir toutes TRPM7 Anticorps
    TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))
    Épitope
    • 15
    • 14
    • 13
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    4th Cytoplasmic Loop
    Reactivité
    • 67
    • 44
    • 32
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    Humain
    Hôte
    • 63
    • 17
    • 2
    • 1
    Lapin
    Clonalité
    • 66
    • 17
    Polyclonal
    Conjugué
    • 34
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TRPM7 est non-conjugé
    Application
    • 79
    • 48
    • 32
    • 18
    • 17
    • 14
    • 11
    • 10
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Specific for TRPM7.
     Réactivité croisée
    Humain, Rat
    Réactivité croisée (Details)
    Other species not yet tested.
    Purification
    IgG
    Immunogène
    A synthetic peptide from the 4th cytoplasmic loop of human TRPM7 (LTRPC7) conjugated to an immunogenic carrier protein was used as the immunogen.
    Isotype
    IgG
    Top Product
    Discover our top product TRPM7 Anticorps primaire
  • Indications d'application
    IHC, WB (confirmed by recombinant protein). A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Conseil sur la manipulation
    Avoid freeze and thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))
    Autre désignation
    TRPM7 (TRPM7 Produits)
    Synonymes
    anticorps cb495, anticorps TRPM7, anticorps chak, anticorps chak1, anticorps ltrpc7, anticorps trp-plik, anticorps ALSPDC, anticorps CHAK, anticorps CHAK1, anticorps LTRPC7, anticorps TRP-PLIK, anticorps 2310022G15Rik, anticorps 4833414K03Rik, anticorps 5033407O22Rik, anticorps LTrpC-7, anticorps Ltpr7, anticorps Ltrpc7, anticorps TRPPLIK, anticorps Chak, anticorps Trp-plik, anticorps transient receptor potential cation channel subfamily M member 7, anticorps transient receptor potential cation channel, subfamily M, member 7, anticorps TRPM7, anticorps trpm7, anticorps Trpm7
    Sujet
    TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants. FUNCTION: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). CATALYTIC ACTIVITY: ATP + a protein: ADP + a phosphoprotein. COFACTOR: Binds 1 zinc ion per subunit. SUBUNIT: Homodimer. Forms heterodimers with TRPM6. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein.,Mammalian TRPM,Transient receptor potential cation channel subfamily M member 7, long transient receptor potential channel 7, LTrpC7, channel-kinase 1, CHAK1, LTRPC7, CHAK, FLJ20117, FLJ25718, TRP-PLIK
    UniProt
    Q96QT4
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