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TLR6 anticorps (N-Term)

TLR6 Reactivité: Humain, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN357054
  • Antigène Voir toutes TLR6 Anticorps
    TLR6 (Toll-Like Receptor 6 (TLR6))
    Épitope
    • 18
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 68
    • 25
    • 3
    • 3
    • 2
    • 1
    • 1
    Humain, Souris
    Hôte
    • 57
    • 19
    • 1
    Lapin
    Clonalité
    • 57
    • 20
    Polyclonal
    Conjugué
    • 38
    • 10
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TLR6 est non-conjugé
    Application
    • 49
    • 45
    • 36
    • 28
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects TLR6 at N-term.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of mouse TLR6.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TLR6 Anticorps primaire
  • Indications d'application
    ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100. Western blot 1: 200 - 1: 500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    TLR6 (Toll-Like Receptor 6 (TLR6))
    Autre désignation
    CD286 / TLR6 (TLR6 Produits)
    Synonymes
    anticorps TLR1, anticorps TLR16, anticorps CD286, anticorps TLR-6, anticorps toll-like receptor 1 family member A, anticorps toll like receptor 6, anticorps toll-like receptor 6, anticorps TLR1A, anticorps TLR6, anticorps Tlr6
    Sujet
    TLR6, a Type I membrane protein that belongs to the Toll-like rceptor family, participates in the innate immune response to Gram-positive bacteria and fungi. It acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. The protein recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It binds to TLR2 via their respective extracellular domains, and to MyD88 via their respective TIR domains. TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.Synonyms: Toll-like receptor 6
    ID gène
    21899, 10090
    UniProt
    Q9EPW9
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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