USP5 anticorps (C-Term)

N° du produit ABIN357529

Détail du produit anti-USP5 anticorps

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody is specific to USP5/ISOT (C-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human USP5.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur USP5

Antigène: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Autre désignation: USP5 / ISOT (USP5 Produits)

Synonymes: anticorps ISOT, anticorps AA407472, anticorps ISOT-1, anticorps Ucht, anticorps ubiquitin specific peptidase 5, anticorps ubiquitin carboxyl-terminal hydrolase 5, anticorps ubiquitin carboxyl-terminal hydrolase 5, putative, anticorps ubiquitin specific protease 5, anticorps ubiquitin specific peptidase 5 (isopeptidase T), anticorps USP5, anticorps CNH02890, anticorps EHI_049940, anticorps CC1G_12961, anticorps MCYG_01862, anticorps CGB_L3600C, anticorps PY00546, anticorps Usp5

Sujet: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 5, Isopeptidase T, Ubiquitin carboxyl-terminal hydrolase 5, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5

Poids moléculaire: 95786 Da

ID gène: 8078, 5874

UniProt: P45974