FNTA anticorps (Middle Region)
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- Antigène Voir toutes FNTA Anticorps
- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FNTA est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects FNTA (Center).
- Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human FNTA.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product FNTA Anticorps primaire
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- Indications d'application
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ELISA: 1/1,000. Western blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
- Autre désignation
- FNTA (FNTA Produits)
- Synonymes
- anticorps ATFTA, anticorps FARNESYLTRANSFERASE A, anticorps FARNESYLTRANSFERASE SUBUNIT A, anticorps PFT/PGGT-IALPHA, anticorps PLP, anticorps PLURIPETALA, anticorps farnesyltransferase A, anticorps FPTA, anticorps PGGT1A, anticorps PTAR2, anticorps PFAS, anticorps FTA, anticorps farnesyltransferase A, anticorps farnesyltransferase, CAAX box, alpha, anticorps FTA, anticorps FNTA, anticorps Fnta
- Sujet
- FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.Synonyms: CAAX farnesyltransferase subunit alpha, FTase-alpha, GGTase-I-alpha, Protein farnesyltransferase / geranylgeranyltransferase type-1 subunit alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha
- Poids moléculaire
- 44408 Da
- ID gène
- 2339, 9606
- UniProt
- P49354
- Pathways
- Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
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