PAD4 anticorps (C-Term)

N° du produit ABIN357799

Détail du produit anti-PAD4 anticorps

Antigène: PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAD4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PAD4 (C-term).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PAD4.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur PAD4

Antigène: PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))

Autre désignation: PADI4 (PADI4 Produits)

Synonymes: anticorps PAD, anticorps PAD4, anticorps PADI5, anticorps PDI4, anticorps PDI5, anticorps Pad4, anticorps Pdi4, anticorps peptidyl arginine deiminase 4, anticorps peptidyl arginine deiminase, type IV, anticorps PADI4, anticorps Padi4

Sujet: PAD4 is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalyzation of the deimination of the arginine residues. PAD4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.Synonyms: HL-60 PAD, PAD4, PADI-H, PADI5, PDI4, PDI5, Peptidylarginine deiminase IV, Protein-arginine deiminase type IV, Protein-arginine deiminase type-4

Poids moléculaire: 74095 Da

ID gène: 23569, 9606

UniProt: Q9UM07