RPS6KA3 anticorps (pSer369)

N° du produit ABIN358394

Détail du produit anti-RPS6KA3 anticorps

Antigène: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Épitope: pSer369

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS6KA3 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Specificité: This antibody detects RPS6KA3 pSer369. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).

Purification: Affinity purification in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S369 of human RPS6KA3.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Dot Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur RPS6KA3

Antigène: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Autre désignation: RPS6KA3 / RSK2 (RPS6KA3 Produits)

Synonymes: anticorps HU-1, anticorps MAPKAPK1A, anticorps RSK, anticorps RSK1, anticorps CLS, anticorps HU-3, anticorps ISPK-1, anticorps MAPKAPK1B, anticorps MRX19, anticorps RSK2, anticorps S6K-alpha3, anticorps p90-RSK2, anticorps pp90RSK2, anticorps MPK-9, anticorps Rsk2, anticorps RGD1563860, anticorps id:ibd1103, anticorps rps6ka3, anticorps si:ch211-114c12.12, anticorps wu:fk86e02, anticorps zgc:56006, anticorps zgc:158386, anticorps ribosomal protein S6 kinase A1, anticorps ribosomal protein S6 kinase A3, anticorps ribosomal protein S6 kinase polypeptide 3, anticorps ribosomal protein S6 kinase a, polypeptide 3a, anticorps ribosomal protein S6 kinase, polypeptide 3b, anticorps RPS6KA1, anticorps RPS6KA3, anticorps Rps6ka3, anticorps rps6ka3a, anticorps rps6ka3b

Sujet: RSK3 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).Synonyms: ISPK-1, ISPK1, MAPKAPK-1b, MAPKAPK1, RSK-2, Ribosomal S6 kinase 2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, p90RSK3

Poids moléculaire: 83736 Da

ID gène: 6197, 9606

UniProt: P51812

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades