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PIK3 gamma anticorps (pSer1100)

PIK3CG Reactivité: Humain EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN358396
  • Antigène Voir toutes PIK3 gamma (PIK3CG) Anticorps
    PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
    Épitope
    • 16
    • 15
    • 15
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1100
    Reactivité
    • 123
    • 23
    • 4
    • 1
    Humain
    Hôte
    • 115
    • 7
    • 1
    Lapin
    Clonalité
    • 115
    • 8
    Polyclonal
    Conjugué
    • 41
    • 12
    • 11
    • 11
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Cet anticorp PIK3 gamma est non-conjugé
    Application
    • 108
    • 66
    • 42
    • 39
    • 39
    • 21
    • 14
    • 9
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects PIK3CG pSer1100.
    Purification
    Affinity purification in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1100 of human PIK3CG.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PIK3CG Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
    Autre désignation
    PIK3CG (PIK3CG Produits)
    Synonymes
    anticorps PI3CG, anticorps PI3K, anticorps PI3Kgamma, anticorps PIK3, anticorps Pi3k, anticorps wu:fb15d07, anticorps zgc:77033, anticorps pi3k, anticorps 5830428L06Rik, anticorps p110gamma, anticorps p120-PI3K, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, anticorps phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma, anticorps si:rp71-17i16.5, anticorps PIK3CG, anticorps Pik3cg, anticorps pik3cg, anticorps si:rp71-17i16.5
    Sujet
    PIK3CG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.Synonyms: 5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, Phosphatidylinositol-4, PtdIns-3-kinase subunit p110-gamma, p120-PI3K
    Poids moléculaire
    126454 Da
    ID gène
    5294, 9606
    UniProt
    P48736
    Pathways
    Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
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