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TERT anticorps (pSer1125)

TERT Reactivité: Humain EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN358472
  • Antigène Voir toutes TERT Anticorps
    TERT (Telomerase Reverse Transcriptase (TERT))
    Épitope
    • 16
    • 16
    • 10
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1125
    Reactivité
    • 105
    • 38
    • 20
    • 5
    • 1
    • 1
    Humain
    Hôte
    • 107
    • 6
    • 1
    Lapin
    Clonalité
    • 98
    • 16
    Polyclonal
    Conjugué
    • 59
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TERT est non-conjugé
    Application
    • 75
    • 55
    • 39
    • 27
    • 17
    • 16
    • 16
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects TERT pSer1125.
    Purification
    Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1125 of human TERT.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TERT Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    TERT (Telomerase Reverse Transcriptase (TERT))
    Autre désignation
    TERT (TERT Produits)
    Synonymes
    anticorps CMM9, anticorps DKCA2, anticorps DKCB4, anticorps EST2, anticorps PFBMFT1, anticorps TCS1, anticorps TP2, anticorps TRT, anticorps hEST2, anticorps hTRT, anticorps chTERT, anticorps Tert, anticorps ATTERT, anticorps F5E19.190, anticorps F5E19_190, anticorps telomerase reverse transcriptase, anticorps tert, anticorps TR, anticorps est2, anticorps tcs1, anticorps telomerase, anticorps tert-A, anticorps tp2, anticorps trt, anticorps xTERT, anticorps telomerase reverse transcriptase, anticorps Telomerase Reverse Transcriptase, anticorps Tertp, anticorps Telomerase catalytic subunit, anticorps telomerase reverse transcriptase L homeolog, anticorps TERT, anticorps trt-1, anticorps Tert, anticorps tert, anticorps CMU_003490, anticorps VDBG_04487, anticorps GL50803_16225, anticorps tert.L
    Sujet
    Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.Synonyms: EST2, HEST2, TCS1, TRT, Telomerase catalytic subunit, Telomerase reverse transcriptase, Telomerase-associated protein 2
    Poids moléculaire
    126997 Da
    ID gène
    7015, 9606
    UniProt
    O14746
    Pathways
    Telomere Maintenance
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