BIRC7 anticorps (C-Term)

N° du produit ABIN358607

Détail du produit anti-BIRC7 anticorps

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to BIRC7.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BIRC7.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western Blot: 1/50 - 1/200. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Références pour anticorps anti-BIRC7 (ABIN358607)

Faruk, Ibrahim, Aminu, Adamu, Abdullahi, Suleiman, Rafindadi, Mohammed, Iliyasu, Idoko, Saidu, Randawa, Musa, Ntekim, Shah, Abubakar, Adoke, Manko, Awasum: "Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin." dans: PLoS ONE, Vol. 16, Issue 1, pp. e0245581, (2021) (PubMed).

Détails sur BIRC7

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Autre désignation: BIRC7 / LIVIN (BIRC7 Produits)

Synonymes: anticorps KIAP, anticorps LIVIN, anticorps ML-IAP, anticorps MLIAP, anticorps RNF50, anticorps EIAP/XLX, anticorps XLX, anticorps kiap, anticorps livin, anticorps ml-iap, anticorps mliap, anticorps rnf50, anticorps xEIAP, anticorps RGD1562883, anticorps zgc:165605, anticorps E130019N06, anticorps Livin, anticorps birc7, anticorps bird7a, anticorps xEIAP/XLX, anticorps xlx, anticorps EIAP/XLX-B, anticorps birc7b, anticorps baculoviral IAP repeat containing 7, anticorps baculoviral IAP repeat-containing 7, anticorps baculoviral IAP repeat-containing 7 (livin), anticorps baculoviral IAP repeat containing 7 S homeolog, anticorps baculoviral IAP repeat containing 7 L homeolog, anticorps BIRC7, anticorps birc7, anticorps Birc7, anticorps birc7.S, anticorps birc7.L

Sujet: BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.Synonyms: Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50

ID gène: 79444, 5874

UniProt: Q96CA5