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MAPK7 anticorps (C-Term)

MAPK7 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN359634
  • Antigène Voir toutes MAPK7 Anticorps
    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
    Épitope
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 14
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 88
    • 62
    • 56
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 119
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 112
    • 11
    Polyclonal
    Conjugué
    • 42
    • 10
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    Cet anticorp MAPK7 est non-conjugé
    Application
    • 76
    • 54
    • 53
    • 43
    • 24
    • 22
    • 16
    • 13
    • 8
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to ERK5.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ERK5.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAPK7 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
    Autre désignation
    MAPK7 / ERK5 (MAPK7 Produits)
    Synonymes
    anticorps BMK1, anticorps ERK4, anticorps ERK5, anticorps PRKM7, anticorps Erk5-T, anticorps ATMPK7, anticorps F8D23.5, anticorps F8D23_5, anticorps MAP kinase 7, anticorps Bmk1, anticorps Erk5, anticorps Prkm7, anticorps ERK-5, anticorps bmk1, anticorps erk4, anticorps mapk7, anticorps prkm7, anticorps mitogen-activated protein kinase 7, anticorps MAP kinase 7, anticorps mitogen-activated protein kinase 7 L homeolog, anticorps MAPK7, anticorps Mapk7, anticorps MPK7, anticorps mapk7.L
    Sujet
    MEK5 and ERK5, a member of the MAP kinase subfamily of the Ser/Thr protein kinases, interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. The second proline-rich region may interact with actin targeting the kinase to a specific location in the cell. ERK5 is autophosphorylated on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent.Synonyms: Big MAP kinase 1, ERK4, Extracellular signal-regulated kinase 5, MAPK7, Mitogen-activated protein kinase 7
    ID gène
    5598, 9606
    UniProt
    Q13164
    Pathways
    Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
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