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FGFR3 anticorps (C-Term)

FGFR3 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN359858
  • Antigène Voir toutes FGFR3 Anticorps
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    Épitope
    • 17
    • 15
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 118
    • 50
    • 42
    • 4
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 111
    • 7
    • 1
    Lapin
    Clonalité
    • 98
    • 21
    Polyclonal
    Conjugué
    • 42
    • 13
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp FGFR3 est non-conjugé
    Application
    • 89
    • 48
    • 47
    • 13
    • 13
    • 10
    • 10
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to FGFR3.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human FGFR3.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product FGFR3 Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    Autre désignation
    CD333 / FGFR3 (FGFR3 Produits)
    Synonymes
    anticorps FGFR3, anticorps LOC100034114, anticorps ACH, anticorps CD333, anticorps CEK2, anticorps HSFGFR3EX, anticorps JTK4, anticorps FR3, anticorps Fgfr-3, anticorps Flg-2, anticorps HBGFR, anticorps Mfr3, anticorps sam3, anticorps fc27h01, anticorps wu:fc27h01, anticorps fibroblast growth factor receptor 3, anticorps fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog, anticorps FGFR3, anticorps fgfr3.S, anticorps Fgfr3, anticorps fgfr3
    Sujet
    FGFR3 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.Synonyms: FGFR-3, Fibroblast growth factor receptor 3, JTK4
    ID gène
    2261, 9606
    UniProt
    P22607
    Pathways
    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
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