HCK anticorps (N-Term)

N° du produit ABIN359984

Détail du produit anti-HCK anticorps

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HCK est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to HCK.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human HCK.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur HCK

Antigène: HCK (Hemopoietic Cell Kinase (HCK))

Autre désignation: HCK (HCK Produits)

Synonymes: anticorps laloo, anticorps HCK, anticorps MGC107870, anticorps JTK9, anticorps p59Hck, anticorps p61Hck, anticorps AI849071, anticorps Bmk, anticorps Hctk, anticorps p56Hck, anticorps HCK proto-oncogene, Src family tyrosine kinase L homeolog, anticorps HCK proto-oncogene, Src family tyrosine kinase, anticorps hemopoietic cell kinase, anticorps hck.L, anticorps HCK, anticorps hck, anticorps Hck

Sujet: HCK is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.Synonyms: B-cell/myeloid kinase, BMK, Hemopoietic cell kinase, Tyrosine-protein kinase HCK, p56-HCK, p59-HCK, p60-HCK

ID gène: 3055, 9606

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling