MEK2 anticorps (Middle Region)

N° du produit ABIN360373

Détail du produit anti-MEK2 anticorps

Antigène: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Épitope: Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to MEK2 (MAP2K2).

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogène: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MAP2K2.

Isotype: Ig Fraction

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur MEK2

Antigène: MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))

Autre désignation: MAPKK 2 (MAP2K2 Produits)

Synonymes: anticorps CFC4, anticorps MAPKK2, anticorps MEK2, anticorps MKK2, anticorps PRKMK2, anticorps AA589381, anticorps MK2, anticorps Prkmk2, anticorps ATMKK2, anticorps F27B13.50, anticorps F27B13_50, anticorps MAP KINASE KINASE 1, anticorps MAP kinase kinase 2, anticorps MK1, anticorps map2k2, anticorps wu:fa56c06, anticorps zgc:123171, anticorps zgc:172250, anticorps mitogen-activated protein kinase kinase 2, anticorps mitogen activated protein kinase kinase 2, anticorps MAP kinase kinase 2, anticorps mitogen-activated protein kinase kinase 2a, anticorps mitogen-activated protein kinase kinase 2b, anticorps MAP2K2, anticorps Map2k2, anticorps MKK2, anticorps map2k2a, anticorps map2k2b

Sujet: MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.Synonyms: Dual specificity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, MAP kinase kinase 2, MAPK/ERK kinase 2, MEK2, MKK2

ID gène: 5605, 9606

UniProt: P36507

Pathways: Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling