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BUB1B anticorps (N-Term)

BUB1B Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN360515
  • Antigène Voir toutes BUB1B Anticorps
    BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
    Épitope
    • 15
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 81
    • 41
    • 11
    • 3
    • 1
    Humain
    Hôte
    • 61
    • 20
    • 8
    Lapin
    Clonalité
    • 66
    • 23
    Polyclonal
    Conjugué
    • 54
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BUB1B est non-conjugé
    Application
    • 70
    • 31
    • 28
    • 23
    • 15
    • 15
    • 13
    • 13
    • 8
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to BUBR1 (BUB1B).
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogène
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BUB1B.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product BUB1B Anticorps primaire
  • Indications d'application
    ELISA: 1/1,000. Western Blot: 1/50 - 1/200. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène
    BUB1B (Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B))
    Autre désignation
    BUB1B (BUB1B Produits)
    Synonymes
    anticorps BUB1beta, anticorps BUBR1, anticorps Bub1A, anticorps MAD3L, anticorps MVA1, anticorps SSK1, anticorps hBUBR1, anticorps AU045529, anticorps bub1b, anticorps BUB1, anticorps BUB1-like, anticorps BubR1, anticorps BubRI, anticorps CG14030, anticorps CG14030/Bub1, anticorps Dmel\\CG14030, anticorps bub1, anticorps BUB1 mitotic checkpoint serine/threonine kinase B, anticorps BUB1B, mitotic checkpoint serine/threonine kinase, anticorps BUB1B, mitotic checkpoint serine/threonine kinase L homeolog, anticorps Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, anticorps Bub1 kinase, anticorps BUB1B, anticorps Bub1b, anticorps bub1b.L, anticorps bub1b, anticorps Bub1
    Sujet
    BUB1B, a member of the Ser/Thr protein kinase family, is a probable component of the mitotic checkpoint that delays anaphase until all chromosomes are properly attached to the mitotic spindle. It can interact with BUB3, CENP-F, CENP-E and mitosin, and can be localized to nuclear kinetochores. This protein is highly expressed in thymus and spleen. The CD1 domain directs kinetochore localization and binding to BUB3. The protein possesses a cyclin destruction box sequence, which targets protein for rapid degradation by ubiquitin-dependent proteolysis during the transition from mitosis to interphase. Defects in BUB1B are associated with tumor formation.Synonyms: BUB1 beta, BUBR1, MAD3/BUB1-related protein kinase, MAD3L, Mitotic checkpoint kinase MAD3L, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, Protein SSK1
    ID gène
    701, 9606
    UniProt
    O60566
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